CLSI H52-A2 (R2016)
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Red Blood Cell Diagnostic Testing Using Flow Cytometry; Approved Guideline – Second Edition, H52A2E
This archived document is no longer being reviewed through the CLSI Consensus Document Development Process. However, this document is technically valid as of January 2021. Because of its value to the laboratory community, it is being retained in CLSI’s library.
This guideline addresses the diagnostic red blood cell (RBC) assays performed as fluorescence-based assays on a flow cytometry platform; including testing procedures for fetomaternal hemorrhage detection, paroxysmal nocturnal hematuria screening, membrane defect anemia testing for hereditary spherocytosis, and nucleated RBC counting. Points of validation and quality control, and caveats of interpretation are also discussed.
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